Selective cytotoxic effects on human breast carcinoma of new methoxylated flavonoids from Euryops arabicus grown in Saudi Arabia
The chloroform–methanol extract of Euryops arabicus, collected from Saudi provenance,
yielded a new kaurane diterpene (1) and seven methoxylated flavones (2–8), two of which
are new (2 and 3). Structures of the compounds were elucidated through interpretation of
spectral data of NMR, MS and comparison with literature values. All compounds were
evaluated for their anti-tumor activities, employing four different cancer cell lines (WI-38,
VERO, HepG2 and MCF-7), ABTS free radical scavenging and immunemodulatory effects …
yielded a new kaurane diterpene (1) and seven methoxylated flavones (2–8), two of which
are new (2 and 3). Structures of the compounds were elucidated through interpretation of
spectral data of NMR, MS and comparison with literature values. All compounds were
evaluated for their anti-tumor activities, employing four different cancer cell lines (WI-38,
VERO, HepG2 and MCF-7), ABTS free radical scavenging and immunemodulatory effects …
